But one of the major advantages was the ability of Nanolive Imaging to capture several biological phenomena and objects at the same time, enabling researchers to observe organelle rotation and other complex cellular dynamics involving multiple subcellular structures. These cell organelles include both membrane and non-membrane bound organelles, present within the cells and are distinct in their structures and functions. The label-free, non-invasive imaging technique meant the team could observe the cells over an extended period of time. The cellular components are called cell organelles. Taken together, the data paints a detailed picture of a cell’s structure and chemical composition, allowing scientists to precisely calculate dry mass, morphology, cell membrane dynamics and other features. Organelles, defined as intracellular membrane-bound structures in eukaryotic cells, were described from the early days of light microscopy and the. They then quantified the observed phenomena using software specially designed to sift through the mass of raw imaging data. In this paper published in PLOS Biology in December 2019 by using Nanolive’s 3D Cell Explorer-fluo, researchers from EPFL could observe changes in cell size during division, organelle movements, and the formation of tiny lipid droplets – all over an extended period and without damaging the cell.
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